An overview of the causes and effects of schizophrenia

These studies ran into difficulties fairly quickly, however, because of the complexity of the relationship between genetic factors and mental illness. Meanwhile, scientists working at the molecular level are exploring the genetic basis for abnormalities in brain development and in the neurotransmitter systems regulating brain function.

Importantly, about a quarter of these children develop schizophrenia that is indistinguishable from idiopathic forms of the illness. Harald Sontheimer, in Diseases of the Nervous System4.

This research has spurred efforts to identify prenatal factors that may have some bearing on the apparent developmental abnormality. Expansions in this third group are usually much longer than those in the first two categories; some repeat several hundred or even several thousand times.

In the s and s, advances in cytogenetic techniques led to the discovery that autism is associated with several different chromosomal abnormalities, including the defect that produces fragile X syndrome.

Overview & Facts

For example, a parent's behavior toward a child diagnosed with depression is partly shaped by the parent's genetic vulnerability to depression. Genetic factors in mental disorders interact with a person's family and cultural environment.

For example, you may have depression and a substance use disorder.

Schizophrenia: An Overview

A major goal of current research on treatments for schizophrenia is to develop a wider variety of long-acting antipsychotics, especially the newer agents with milder side effects, which can be delivered through injection. Risk factors Certain factors may increase your risk of developing mental health problems, including: Education can help friends and family understand the disorder and be more compassionate with the person who has it.


A copy of the report may be ordered by faxing the Superintendent of Documents at In the near future, researchers hope to devise genetic tests that will measure patients'responsiveness to specific antidepressant and anti-anxiety medications.

Family studies Family studies are important tools for evaluating environmental effects on children with genetic disorders— and also for evaluating the impact of the disorder on the family environment. In addition to any of these adherence strategies, patient and family education about schizophrenia, its symptoms, and the medications being prescribed to treat the disease is an important part of the treatment process and helps support the rationale for good adherence.

It is difficult to predict which patients will fall into these two groups and to distinguish them from the large majority of patients who do benefit from treatment with antipsychotic drugs.

Genetic factors and mental disorders

The discovery of expansion mutations was the solution to a long-standing genetic riddle. There are several terms in biological psychiatry that are important to understand:Get an overview of abdominal hernia symptoms, types, surgery, repair, pain, and diet.

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Antipsychotic drug treatment is a key component of schizophrenia treatment algorithms recommended by the National Institute of Health and Care Excellence (NICE), the American Psychiatric Association, and the British Society for Psychopharmacology. The main effect of treatment with antipsychotics is to reduce the so-called "positive" symptoms, including delusions and hallucinations.

Nov 05,  · Schizophrenia: A Brief Overview By Donald Graber, M.D. Because schizophrenia causes significant struggles in perceiving reality accurately, it strongly Unfortunately, significant possible side effects of these typical (or “first generation”) antipsychotics include disordered movement, muscle rigidity, and.

Schizophrenia Information > What Causes Schizophrenia?: The Causes of Schizophrenia: Introduction to the Causes of Schizophrenia; Genetic Contribution to Schizophrenia. Schizophrenia Symptoms, Signs, and Coping Tips How to Recognize Schizophrenia and Get the Help You Need.

Paranoia and schizophrenia: What you need to know

Schizophrenia is a challenging disorder that often makes it difficult to distinguish between what is real and unreal, to think clearly, manage emotions, relate to others, and function normally.

Paranoid schizophrenia is characterized by predominantly positive symptoms of schizophrenia, including delusions and hallucinations.

These debilitating symptoms blur the line between what is real and what isn’t, making it difficult for the person to lead a typical life.

An overview of the causes and effects of schizophrenia
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